diff --git a/gtk/gtklistitem.c b/gtk/gtklistitem.c
index 267b9ea6c5..a06a43a28d 100644
--- a/gtk/gtklistitem.c
+++ b/gtk/gtklistitem.c
@@ -22,6 +22,7 @@
 #include "gtklistitemprivate.h"
 
 #include "gtkcolumnviewcell.h"
+#include "gtkaccessible.h"
 
 /**
  * GtkListItem:
@@ -45,6 +46,8 @@
 enum
 {
   PROP_0,
+  PROP_ACCESSIBLE_DESCRIPTION,
+  PROP_ACCESSIBLE_LABEL,
   PROP_ACTIVATABLE,
   PROP_CHILD,
   PROP_FOCUSABLE,
@@ -68,6 +71,9 @@ gtk_list_item_dispose (GObject *object)
   g_assert (self->owner == NULL); /* would hold a reference */
   g_clear_object (&self->child);
 
+  g_clear_pointer (&self->accessible_description, g_free);
+  g_clear_pointer (&self->accessible_label, g_free);
+
   G_OBJECT_CLASS (gtk_list_item_parent_class)->dispose (object);
 }
 
@@ -81,6 +87,14 @@ gtk_list_item_get_property (GObject    *object,
 
   switch (property_id)
     {
+    case PROP_ACCESSIBLE_DESCRIPTION:
+      g_value_set_string (value, self->accessible_description);
+      break;
+
+    case PROP_ACCESSIBLE_LABEL:
+      g_value_set_string (value, self->accessible_label);
+      break;
+
     case PROP_ACTIVATABLE:
       g_value_set_boolean (value, self->activatable);
       break;
@@ -132,6 +146,14 @@ gtk_list_item_set_property (GObject      *object,
 
   switch (property_id)
     {
+    case PROP_ACCESSIBLE_DESCRIPTION:
+      gtk_list_item_set_accessible_description (self, g_value_get_string (value));
+      break;
+
+    case PROP_ACCESSIBLE_LABEL:
+      gtk_list_item_set_accessible_label (self, g_value_get_string (value));
+      break;
+
     case PROP_ACTIVATABLE:
       gtk_list_item_set_activatable (self, g_value_get_boolean (value));
       break;
@@ -163,6 +185,30 @@ gtk_list_item_class_init (GtkListItemClass *klass)
   gobject_class->get_property = gtk_list_item_get_property;
   gobject_class->set_property = gtk_list_item_set_property;
 
+  /**
+   * GtkListItem:accessible-description: (attributes org.gtk.Property.get=gtk_list_item_get_accessible_description org.gtk.Property.set=gtk_list_item_set_accessible_description)
+   *
+   * The accessible description to set on the list item.
+   *
+   * Since: 4.12
+   */
+  properties[PROP_ACCESSIBLE_DESCRIPTION] =
+    g_param_spec_string ("accessible-description", NULL, NULL,
+                         NULL,
+                         G_PARAM_READWRITE | G_PARAM_EXPLICIT_NOTIFY | G_PARAM_STATIC_STRINGS);
+
+  /**
+   * GtkListItem:accessible-label: (attributes org.gtk.Property.get=gtk_list_item_get_accessible_label org.gtk.Property.set=gtk_list_item_set_accessible_label)
+   *
+   * The accessible label to set on the list item.
+   *
+   * Since: 4.12
+   */
+  properties[PROP_ACCESSIBLE_LABEL] =
+    g_param_spec_string ("accessible-label", NULL, NULL,
+                         NULL,
+                         G_PARAM_READWRITE | G_PARAM_EXPLICIT_NOTIFY | G_PARAM_STATIC_STRINGS);
+
   /**
    * GtkListItem:activatable: (attributes org.gtk.Property.get=gtk_list_item_get_activatable org.gtk.Property.set=gtk_list_item_set_activatable)
    *
@@ -562,3 +608,93 @@ gtk_list_item_set_focusable (GtkListItem *self,
 
   g_object_notify_by_pspec (G_OBJECT (self), properties[PROP_FOCUSABLE]);
 }
+
+/**
+ * gtk_list_item_set_accessible_description:
+ * @self: a `GtkListItem`
+ * @description: the description
+ *
+ * Sets the accessible description for the list item,
+ * which may be used by e.g. screen readers.
+ *
+ * Since: 4.12
+ */
+void
+gtk_list_item_set_accessible_description (GtkListItem *self,
+                                          const char  *description)
+{
+  g_return_if_fail (GTK_IS_LIST_ITEM (self));
+
+  if (!g_set_str (&self->accessible_description, description))
+    return;
+
+  if (self->owner)
+    gtk_accessible_update_property (GTK_ACCESSIBLE (self->owner),
+                                    GTK_ACCESSIBLE_PROPERTY_DESCRIPTION, self->accessible_description,
+                                    -1);
+
+  g_object_notify_by_pspec (G_OBJECT (self), properties[PROP_ACCESSIBLE_DESCRIPTION]);
+}
+
+/**
+ * gtk_list_item_get_accessible_description:
+ * @self: a `GtkListItem`
+ *
+ * Gets the accessible description of @self.
+ *
+ * Returns: the accessible description
+ *
+ * Since: 4.12
+ */
+const char *
+gtk_list_item_get_accessible_description (GtkListItem *self)
+{
+  g_return_val_if_fail (GTK_IS_LIST_ITEM (self), NULL);
+
+  return self->accessible_description;
+}
+
+/**
+ * gtk_list_item_set_accessible_label:
+ * @self: a `GtkListItem`
+ * @label: the label
+ *
+ * Sets the accessible label for the list item,
+ * which may be used by e.g. screen readers.
+ *
+ * Since: 4.12
+ */
+void
+gtk_list_item_set_accessible_label (GtkListItem *self,
+                                    const char  *label)
+{
+  g_return_if_fail (GTK_IS_LIST_ITEM (self));
+
+  if (!g_set_str (&self->accessible_label, label))
+    return;
+
+  if (self->owner)
+    gtk_accessible_update_property (GTK_ACCESSIBLE (self->owner),
+                                    GTK_ACCESSIBLE_PROPERTY_LABEL, self->accessible_label,
+                                    -1);
+
+  g_object_notify_by_pspec (G_OBJECT (self), properties[PROP_ACCESSIBLE_LABEL]);
+}
+
+/**
+ * gtk_list_item_get_accessible_label:
+ * @self: a `GtkListItem`
+ *
+ * Gets the accessible label of @self.
+ *
+ * Returns: the accessible label
+ *
+ * Since: 4.12
+ */
+const char *
+gtk_list_item_get_accessible_label (GtkListItem *self)
+{
+  g_return_val_if_fail (GTK_IS_LIST_ITEM (self), NULL);
+
+  return self->accessible_label;
+}
diff --git a/gtk/gtklistitem.h b/gtk/gtklistitem.h
index 9c5fb844e1..5ce8d8e5d1 100644
--- a/gtk/gtklistitem.h
+++ b/gtk/gtklistitem.h
@@ -59,5 +59,17 @@ void            gtk_list_item_set_child                         (GtkListItem
 GDK_AVAILABLE_IN_ALL
 GtkWidget *     gtk_list_item_get_child                         (GtkListItem            *self);
 
+GDK_AVAILABLE_IN_4_12
+void            gtk_list_item_set_accessible_description        (GtkListItem            *self,
+                                                                 const char             *description);
+GDK_AVAILABLE_IN_4_12
+const char *    gtk_list_item_get_accessible_description        (GtkListItem            *self);
+
+GDK_AVAILABLE_IN_4_12
+void            gtk_list_item_set_accessible_label              (GtkListItem            *self,
+                                                                 const char             *label);
+GDK_AVAILABLE_IN_4_12
+const char *    gtk_list_item_get_accessible_label              (GtkListItem            *self);
+
 G_END_DECLS
 
diff --git a/gtk/gtklistitemprivate.h b/gtk/gtklistitemprivate.h
index 60e122bc10..91900472aa 100644
--- a/gtk/gtklistitemprivate.h
+++ b/gtk/gtklistitemprivate.h
@@ -35,6 +35,9 @@ struct _GtkListItem
 
   GtkWidget *child;
 
+  char *accessible_label;
+  char *accessible_description;
+
   guint activatable : 1;
   guint selectable : 1;
   guint focusable : 1;
diff --git a/gtk/gtklistitemwidget.c b/gtk/gtklistitemwidget.c
index b5fac6f7b8..8c92de5e79 100644
--- a/gtk/gtklistitemwidget.c
+++ b/gtk/gtklistitemwidget.c
@@ -120,6 +120,11 @@ gtk_list_item_widget_setup_object (GtkListFactoryWidget *fw,
   gtk_list_factory_widget_set_selectable (fw, list_item->selectable);
   gtk_widget_set_focusable (GTK_WIDGET (self), list_item->focusable);
 
+  gtk_accessible_update_property (GTK_ACCESSIBLE (self),
+                                  GTK_ACCESSIBLE_PROPERTY_LABEL, list_item->accessible_label,
+                                  GTK_ACCESSIBLE_PROPERTY_DESCRIPTION, list_item->accessible_description,
+                                  -1);
+
   gtk_list_item_do_notify (list_item,
                            gtk_list_item_base_get_item (GTK_LIST_ITEM_BASE (self)) != NULL,
                            gtk_list_item_base_get_position (GTK_LIST_ITEM_BASE (self)) != GTK_INVALID_LIST_POSITION,