diff --git a/.github/workflows/pypi.yml b/.github/workflows/pypi.yml
new file mode 100644
index 0000000..d3a16af
--- /dev/null
+++ b/.github/workflows/pypi.yml
@@ -0,0 +1,49 @@
+name: PyPI
+on:
+  push:
+    paths:
+    - .github/workflows/pypi.yml
+    - LICENSE
+    - python_appimage
+    - README.md
+    - setup.py
+
+jobs:
+  Test:
+    runs-on: ubuntu-latest
+    strategy:
+      matrix:
+        version: ['2.7', '3.5']
+
+    steps:
+    - uses: actions/checkout@v2
+    - uses: actions/setup-python@v1
+      with:
+        python-version: ${{ matrix.version }}
+
+    - name: Test local builder
+      run: |
+        python -m python_appimage local -p $(which python) -d test.AppImage
+        test -e test.AppImage
+
+  Publish:
+    needs: Test
+    runs-on: ubuntu-latest
+
+    steps:
+    - uses: actions/checkout@v2
+    - uses: actions/setup-python@v1
+      with:
+        python-version: '3.8'
+
+    - name: Build wheel
+      run: |
+        pip install -U pip
+        pip install -U wheel
+        python setup.py bdist_wheel --universal
+
+    - name: Upload to PyPI
+      if: github.ref == 'refs/heads/master'
+      uses: pypa/gh-action-pypi-publish@master
+      with:
+        password: ${{ secrets.PYPI_TOKEN }}
diff --git a/.gitignore b/.gitignore
index 379fe5c..2db725d 100644
--- a/.gitignore
+++ b/.gitignore
@@ -3,5 +3,9 @@
 *.pyo
 __pycache__
 AppDir
+build
+dist
+python_appimage.egg-info
 python_appimage/bin
 python_appimage/data/excludelist
+python_appimage/version.py
diff --git a/setup.py b/setup.py
new file mode 100644
index 0000000..1baf277
--- /dev/null
+++ b/setup.py
@@ -0,0 +1,97 @@
+import json
+import os
+import setuptools
+import ssl
+import subprocess
+try:
+    from urllib.request import urlopen
+except ImportError:
+    from urllib2 import urlopen
+
+from python_appimage.utils.deps import fetch_all
+
+
+CLASSIFIERS = '''\
+Development Status :: 4 - Beta
+Intended Audience :: Developers
+License :: OSI Approved :: GNU General Public License v3 (GPLv3)
+Programming Language :: Python
+Topic :: Software Development
+Operating System :: POSIX :: Linux
+'''
+
+
+with open('README.md') as f:
+    long_description = f.read()
+
+
+def get_version():
+    '''Get the next version number from PyPI
+    '''
+    version = os.getenv('PYTHON_APPIMAGE_VERSION')
+    if not version:
+        try:
+            _create_unverified_https_context = ssl._create_unverified_context
+        except AttributeError:
+            pass
+        else:
+            ssl._create_default_https_context = _create_unverified_https_context
+
+        meta = json.load(
+                urlopen('https://pypi.org/pypi/python-appimage/json'))
+
+        version = meta['info']['version']
+        numbers = version.split('.')
+        numbers[-1] = str(int(numbers[-1]) + 1)
+        version = '.'.join(numbers)
+
+    p = subprocess.Popen('git describe --match=NeVeRmAtCh --always --dirty',
+                       shell=True, stdout=subprocess.PIPE,
+                       stderr=subprocess.STDOUT)
+    stdout, _ = p.communicate()
+    try:
+        stdout = stdout.decode()
+    except AttributeError:
+        stdout = str(stdout)
+    git_revision = stdout.strip()
+
+    with open('python_appimage/version.py', 'w+') as f:
+        f.write('''\
+# This file was generated by setup.py
+version = '{version:}'
+git_revision = '{git_revision:}'
+'''.format(version=version, git_revision=git_revision))
+
+    return version
+
+
+def get_package_data():
+    '''Get the list of package data
+    '''
+    prefix = os.path.dirname(__file__) or '.'
+    return ['data/' + file_
+            for file_ in os.listdir(prefix + '/python_appimage/data')]
+
+
+setuptools.setup(
+    name = 'python_appimage',
+    version = get_version(),
+    author = 'Valentin Niess',
+    author_email = 'valentin.niess@gmail.com',
+    description = 'Appimage releases of Python',
+    long_description = long_description,
+    long_description_content_type = 'text/markdown',
+    url = 'https://github.com/niess/python-appimage',
+    download_url = 'https://pypi.python.org/pypi/python-appimage',
+    project_urls = {
+        'Bug Tracker' : 'https://github.com/niess/python-appimage/issues',
+        'Source Code' : 'https://github.com/niess/python-appimage',
+    },
+    packages = setuptools.find_packages(),
+    classifiers = [s for s in CLASSIFIERS.split(os.linesep) if s.strip()],
+    license = 'GPLv3',
+    platforms = ['Linux'],
+    python_requires = '>=2.7',
+    include_package_data = True,
+    package_data = {'': get_package_data()}
+)